These are relatively mainstream, so I would imagine that you're already familiar with them, but I thought I'd mention them anyway for anyone who isn't already familiar:Archer
The story of ISIS, a top-secret privatized spy organization and its top agent, Sterling Archer - an oafish, womanizing, alcoholic, misogynistic James Bond analogue who is just perfect. Voiced by an all-star cast, including a number of the cast of cult classic TV show "Arrested Development".The Venture Bros.
A parody of basically all of the 'for-kids' action comics and cartoons of the 60's - particularly Jonny Quest and the Hardy Boys. Revolves around the eponymous Venture brothers, Hank and Dean, as well as their father, washed-up super scientist Thaddeus Venture and their "Half-Swedish Killing Machine" bodyguard, Brock Samson, as well as one of the best Rogues' Galleries in contemporary television, predominantly "The Monarch" and his partner in crime/girlfriend "Dr. Girlfriend".
For Japanese cartoons, I recommend:Death Note
The story of a bored supra-genius university student who comes into possession of a grim reaper's notebook - a magical item that instantly kills anyone whose name is written into it. Blurs the boundaries between good and evil as you follow the antagonist in his crusade to create a perfect world, free of crime but ruled by fear of divine retribution.Berserk
(Site in Japanese)
An epic medieval fantasy tale of a young warrior named Guts, who joins a band of mercenaries called the "Band of the Hawk", led by charismatic, megalomaniacal would-be knight king Griffith on a quest of honor, betrayal, love and loss. Not for the faint of heart. The cartoon series is a little old, but is being remade as an animated film soon. The comic is still in publication, with as of this writing 35 books averaging roughly 250+ pages each.