Love the visuals, and it's fun to see character with an asymmetric style. 
Indeed, this is going to be a nightmare to animate - doing all animations twice...
Twice is a bit of an exaggeration, frames just can't be flipped horizontally without tweaking the head

Kathy Rain was a bit more difficult, since the asymmetry for her was prevalent over the entire sprite, not just the head. It still wasn't as much work as you'd think though, as many animations were drawn for a single direction anyway.
With that being said, since we are in somewhat uncharted waters with the bump to 640x360, we ARE
looking for an additional animator to help alleviate the workload!