I've been thinking about making a comic-book style game with AGS that actually looks like a comic book - as in, still panels rather than rooms. This is mainly because I can't animate to save my life, but I also think it would be beneficial to the game experience as a whole. While some people spend a lot of time on animating their graphics and less on creating detailed closeup images of important objects, an interactive graphic novel would be able to focus all of that on creating lots of individual panels for every single thing.
It's hard to articulate what I'm talking about here. I'll see if I can't throw together a tech demo within the next few days.
Let me introduce you to the great Comix Zone: http://www.the-underdogs.org/game.php?id=1671
I'd like to see this.
But...with a text parser. Not point and click or choose-your-own adventure.
Okay, maybe this is showing my age too much, but...
I absolutely loved Lane Mastodon versus the Blubbermen back in the day. 8)