Keyboard control (Arrow Keys and other buttons)

[Sir Bob]

Is there a way to change a game so that the arrow keys are used for movement and  other buttons are used for talking/walking/etc. to somthing that you are facing?

[Ashen]

With AGS, all things are possible ...

You may be interested in strazer & Rui's Keyboard Movement Module (for obvious reasons).

For the rest ... I suppose regions/hotspots could be used to check where the character is, and on_key_press() used to carry out the interaction. Depends on how exactly you want it to work, but yes, it's certainly possible. Magintz's Text Parser Template might give you some ideas on working without a mouse.