I am having the exact same problem with Space Quest 4.5 on my Windows 7 x64 laptop. SQ4.5 uses AGS 2.72.920. However, I also installed Space Quest 2 VGA, which uses AGS 3.21.1115, and it works just fine.
Oddly, the cutscenes play if I hold down the mouse on the window title bar, or if I right-click on the title bar but don't dismiss the popup menu.
However, AGS is actually responding to the mouse. When the narrator starts speaking, I can click inside the game window and the speech is skipped, as expected. Whenever the mouse moves around inside the game window, the game is tracking the cursor position correctly. But, since the game window is not rendering onscreen correctly, I don't see the cursor moving around the screen unless I force a repaint, such as by switching to another window and then back to the game. The game cursor is then rendered where the mouse was last seen.
The window just won't render while it is the active foreground window, unless the mouse is held down on the title bar, or right-clicking on the title bar.
Oddly, if I right-click on the window title, choose "Move", and then click inside the game window, everything starts working correctly! The cutscenes play normally, the game cursor follows the mouse, etc.
Oddly, the cutscenes play if I hold down the mouse on the window title bar, or if I right-click on the title bar but don't dismiss the popup menu.
However, AGS is actually responding to the mouse. When the narrator starts speaking, I can click inside the game window and the speech is skipped, as expected. Whenever the mouse moves around inside the game window, the game is tracking the cursor position correctly. But, since the game window is not rendering onscreen correctly, I don't see the cursor moving around the screen unless I force a repaint, such as by switching to another window and then back to the game. The game cursor is then rendered where the mouse was last seen.
The window just won't render while it is the active foreground window, unless the mouse is held down on the title bar, or right-clicking on the title bar.
Oddly, if I right-click on the window title, choose "Move", and then click inside the game window, everything starts working correctly! The cutscenes play normally, the game cursor follows the mouse, etc.