Clearly a little bit tooooooooo cryptic. 
Hint:
Plagued (5): What was a typical vector for this specific disease?
Sailor (6): Bit of word play.... What does a sailor do that defines him in the popular imagination?

Hint:
Spoiler
Plagued (5): What was a typical vector for this specific disease?
Sailor (6): Bit of word play.... What does a sailor do that defines him in the popular imagination?
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