If you don't like low-res text and mouse movement, don't make a low-res game. 
Also, I've said it before, AGS needs to abolish fullscreen mode and just upscale the game image to the user's current screen resolution. Most screens these days are designed to look good at one specific resolution and nothing else.

Also, I've said it before, AGS needs to abolish fullscreen mode and just upscale the game image to the user's current screen resolution. Most screens these days are designed to look good at one specific resolution and nothing else.